Assay Detail
Functional
CHEMBL1109172
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Antiplasmodial activity against Plasmodium falciparum
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiplasmodial lanostanes from the Ganoderma lucidum mushroom.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.91 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1097153 | GANODERIC ALDEHYDE TR | — | 1 | 5.22 |
| CHEMBL1097547 | — | — | 1 | 4.96 |
| CHEMBL1097154 | GANODERIC ACID S | — | 1 | 4.96 |
| CHEMBL1098479 | GANODERMANONDIOL | — | 1 | 4.89 |
| CHEMBL1095857 | GANODERIC ACID TR 1 | — | 1 | 4.75 |
| CHEMBL1097474 | GANODERIC ACID TR | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1097153 | GANODERIC ALDEHYDE TR | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL1097547 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL1097154 | GANODERIC ACID S | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL1098479 | GANODERMANONDIOL | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL1095857 | GANODERIC ACID TR 1 | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL1097474 | GANODERIC ACID TR | IC50 | = | 20000.0 | nM | 4.70 |