Assay Detail
Binding
CHEMBL1109339
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Inhibition of HIV1 protease
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of the dimerization and active site of HIV-1 protease by secondary metabolites from the Vietnamese mushroom Ganoderma colossum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.31 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL484853 | CARNOSIC ACID | — | 1 | 6.62 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL484853 | CARNOSIC ACID | IC50 | = | 240.0 | nM | 6.62 |
| CHEMBL140 | CURCUMIN | IC50 | = | 100000.0 | nM | 4.00 |