Assay Detail
Binding
CHEMBL1111005
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Noncompetitive inhibition of Clostridium perfringens neuraminidase
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Clostridium perfringens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Prenylated pterocarpans as bacterial neuraminidase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 5.66 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1086764 | ERYSUBIN E | — | 1 | 6.62 |
| CHEMBL454849 | ERYTHRABYSSIN I | — | 1 | 6.51 |
| CHEMBL1096406 | ERYTHRIBYSSIN O | — | 1 | 5.92 |
| CHEMBL1088321 | SOPHORAPTEROCARPAN A | — | 1 | 5.75 |
| CHEMBL1088462 | ERYSTAGALLIN A | — | 1 | 5.75 |
| CHEMBL1096407 | CALOPOCARPIN | — | 1 | 5.68 |
| CHEMBL1097045 | ERYVARIN D | — | 1 | 5.59 |
| CHEMBL1098413 | DEMETHYLMEDICARPIN | — | 1 | 5.42 |
| CHEMBL1096408 | ERYTHRIBYSSIN L | — | 1 | 5.38 |
| CHEMBL1098729 | ISONEORAUTENOL | — | 1 | 4.96 |
| CHEMBL1098728 | NEORAUTENOL | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1086764 | ERYSUBIN E | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL454849 | ERYTHRABYSSIN I | Ki | = | 310.0 | nM | 6.51 |
| CHEMBL1096406 | ERYTHRIBYSSIN O | Ki | = | 1210.0 | nM | 5.92 |
| CHEMBL1088321 | SOPHORAPTEROCARPAN A | Ki | = | 1780.0 | nM | 5.75 |
| CHEMBL1088462 | ERYSTAGALLIN A | Ki | = | 1800.0 | nM | 5.75 |
| CHEMBL1096407 | CALOPOCARPIN | Ki | = | 2090.0 | nM | 5.68 |
| CHEMBL1097045 | ERYVARIN D | Ki | = | 2550.0 | nM | 5.59 |
| CHEMBL1098413 | DEMETHYLMEDICARPIN | Ki | = | 3830.0 | nM | 5.42 |
| CHEMBL1096408 | ERYTHRIBYSSIN L | Ki | = | 4130.0 | nM | 5.38 |
| CHEMBL1098729 | ISONEORAUTENOL | Ki | = | 10960.0 | nM | 4.96 |
| CHEMBL1098728 | NEORAUTENOL | Ki | = | 21740.0 | nM | 4.66 |