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Assay Detail

CHEMBL1111006

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Competitive inhibition of Clostridium perfringens neuraminidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Clostridium perfringens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sialidase (CHEMBL5189)
Type SINGLE PROTEIN
Organism Clostridium perfringens

Publication

Prenylated pterocarpans as bacterial neuraminidase inhibitors.
Nguyen PH, Nguyen TN, Kang KW, Ndinteh DT, Mbafor JT, Kim YR, Oh WK.
Bioorg Med Chem (2010) 18 : 3335 -3344
PubMed 20363636 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.07 5.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL448350 PHASEOLIN 1 5.32
CHEMBL1095422 ERYSUBIN D 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL448350 PHASEOLIN Ki = 4840.0 nM 5.32
CHEMBL1095422 ERYSUBIN D Ki = 15200.0 nM 4.82