Assay Detail
Binding
CHEMBL1114350
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Inhibition of potato 5LOX by enzyme immuno assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Solanum tuberosum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.97 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1092137 | — | — | 1 | 6.60 |
| CHEMBL1089959 | — | — | 1 | 6.36 |
| CHEMBL1092135 | — | — | 1 | 6.34 |
| CHEMBL1089958 | — | — | 1 | 6.11 |
| CHEMBL1092138 | — | — | 1 | 5.52 |
| CHEMBL1092136 | — | — | 1 | 5.43 |
| CHEMBL145 | CAFFEIC ACID | 3.0 | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1092137 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1089959 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL1092135 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL1089958 | — | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL1092138 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1092136 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL145 | CAFFEIC ACID | IC50 | = | 4000.0 | nM | 5.40 |