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Assay Detail

CHEMBL1114609

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Plasmodium falciparum S-adenosyl-homocysteine hydrolase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Plasmodium falciparum
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Adenosylhomocysteinase (CHEMBL6076)
Type SINGLE PROTEIN
Organism Plasmodium falciparum 3D7

Publication

A new structural class of S-adenosylhomocysteine hydrolase inhibitors.
Kim BG, Chun TG, Lee HY, Snapper ML.
Bioorg Med Chem (2009) 17 : 6707 -6714
PubMed 19692248 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL129014 NORARISTEROMYCIN 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL129014 NORARISTEROMYCIN IC50 = 1100.0 nM 5.96