Assay Detail
Functional
CHEMBL1115069
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Inhibition of HCV 1b NS5B Cdelta21 RNA dependent RNA polymerase expressed in Escherichia coli after 30 mins by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis C virus subtype 1b |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.77 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1093511 | — | — | 1 | 5.30 |
| CHEMBL1088991 | — | — | 1 | 4.52 |
| CHEMBL159895 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1093511 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1088991 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL159895 | — | IC50 | = | 33000.0 | nM | 4.48 |