Assay Detail
Functional
CHEMBL1116163
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Cytotoxicity against human PC3 cells after 72 hrs by WST-8 assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Efficient microwave-assisted prenylation of pinostrobin and biological evaluation of its derivatives as antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.44 | 4.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1092923 | — | — | 1 | 4.98 |
| CHEMBL1092922 | — | — | 1 | 4.55 |
| CHEMBL1089227 | — | — | 1 | 4.45 |
| CHEMBL1091661 | — | — | 1 | 4.42 |
| CHEMBL1088927 | — | — | 1 | 4.34 |
| CHEMBL1093176 | — | — | 1 | 4.34 |
| CHEMBL1093177 | — | — | 1 | 4.34 |
| CHEMBL254613 | PINOSTROBIN | — | 1 | 4.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1092923 | — | IC50 | = | 10400.0 | nM | 4.98 |
| CHEMBL1092922 | — | IC50 | = | 28400.0 | nM | 4.55 |
| CHEMBL1089227 | — | IC50 | = | 35300.0 | nM | 4.45 |
| CHEMBL1091661 | — | IC50 | = | 37800.0 | nM | 4.42 |
| CHEMBL1088927 | — | IC50 | = | 45800.0 | nM | 4.34 |
| CHEMBL1093176 | — | IC50 | = | 45300.0 | nM | 4.34 |
| CHEMBL1093177 | — | IC50 | = | 46000.0 | nM | 4.34 |
| CHEMBL254613 | PINOSTROBIN | IC50 | = | 86700.0 | nM | 4.06 |