Assay Detail
Functional
CHEMBL1116337
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Cytotoxicity against human Saos2 cells after 48 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SAOS-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic naphthoquinones from Alkanna cappadocica ( perpendicular).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.30 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL513640 | — | — | 1 | 6.08 |
| CHEMBL486627 | DEOXYSHIKONIN | — | 1 | 6.07 |
| CHEMBL28457 | ALKANNIN | — | 1 | 5.64 |
| CHEMBL112415 | ACETYLALKANNIN | — | 1 | 5.31 |
| CHEMBL1097731 | — | — | 1 | 4.90 |
| CHEMBL1097732 | — | — | 1 | 4.86 |
| CHEMBL1096404 | — | — | 1 | 4.84 |
| CHEMBL1099068 | — | — | 1 | 4.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL513640 | — | IC50 | = | 840.0 | nM | 6.08 |
| CHEMBL486627 | DEOXYSHIKONIN | IC50 | = | 850.0 | nM | 6.07 |
| CHEMBL28457 | ALKANNIN | IC50 | = | 2310.0 | nM | 5.64 |
| CHEMBL112415 | ACETYLALKANNIN | IC50 | = | 4930.0 | nM | 5.31 |
| CHEMBL1097731 | — | IC50 | = | 12510.0 | nM | 4.90 |
| CHEMBL1097732 | — | IC50 | = | 13810.0 | nM | 4.86 |
| CHEMBL1096404 | — | IC50 | = | 14480.0 | nM | 4.84 |
| CHEMBL1099068 | — | IC50 | = | 20410.0 | nM | 4.69 |