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Assay Detail

CHEMBL1120076

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of 8-anilino-1-naphthalene-sulfonic acid from human FABP4 F16A mutant expressed in Escherichia coli BL21 (DE3) cells after 3 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type BL21-DE3
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening.
Cai H, Yan G, Zhang X, Gorbenko O, Wang H, Zhu W.
Bioorg Med Chem Lett (2010) 20 : 3675 -3679
PubMed 20471252 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.12 4.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1085571 1 4.12
CHEMBL1085570 1 -
CHEMBL267476 LINOLEIC ACID 2.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1085571 IC50 = 76500.0 nM 4.12
CHEMBL1085570 IC50 - -
CHEMBL267476 LINOLEIC ACID IC50 - -