Assay Detail
Binding
CHEMBL1120184
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Inhibition of HIV integrase strand transfer activity
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.58 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217285 | — | — | 1 | 5.58 |
| CHEMBL1084171 | — | — | 1 | - |
| CHEMBL1082495 | — | — | 1 | - |
| CHEMBL1086318 | — | — | 1 | - |
| CHEMBL1085363 | — | — | 1 | - |
| CHEMBL1085364 | — | — | 1 | - |
| CHEMBL1085365 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217285 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL1084171 | — | IC50 | = | 111000.0 | nM | - |
| CHEMBL1082495 | — | IC50 | = | 169000.0 | nM | - |
| CHEMBL1086318 | — | IC50 | = | 206000.0 | nM | - |
| CHEMBL1085363 | — | IC50 | > | 333000.0 | nM | - |
| CHEMBL1085364 | — | IC50 | = | 243000.0 | nM | - |
| CHEMBL1085365 | — | IC50 | = | 241000.0 | nM | - |