Assay Detail
Binding
CHEMBL1120573
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Inhibition of integrin alphaVbeta3
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Emerging targets in osteoporosis disease modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 9.13 | 10.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL145085 | — | — | 1 | 10.10 |
| CHEMBL1083695 | — | — | 1 | 9.72 |
| CHEMBL179069 | — | — | 1 | 9.62 |
| CHEMBL369981 | — | — | 1 | 9.40 |
| CHEMBL228605 | — | — | 1 | 9.30 |
| CHEMBL429876 | CILENGITIDE | 3.0 | 1 | 9.22 |
| CHEMBL1083696 | — | — | 1 | 6.52 |
| CHEMBL378530 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL145085 | — | IC50 | = | 0.08 | nM | 10.10 |
| CHEMBL1083695 | — | IC50 | = | 0.19 | nM | 9.72 |
| CHEMBL179069 | — | IC50 | = | 0.24 | nM | 9.62 |
| CHEMBL369981 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL228605 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL429876 | CILENGITIDE | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL1083696 | — | IC50 | = | 304.0 | nM | 6.52 |
| CHEMBL378530 | — | IC50 | = | 30.0 | nM | - |