Assay Detail
Functional
CHEMBL1121048
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Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum Dd2 after 72 hrs by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.81 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 7.68 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.89 |
| CHEMBL1095507 | PSAMMAPLYSIN F | — | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269671 | ARTEMISININ | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL76 | CHLOROQUINE | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL1095507 | PSAMMAPLYSIN F | IC50 | = | 1400.0 | nM | 5.85 |