Assay Detail
Functional
CHEMBL1121089
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Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7 by micro dilution assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The bisnaphthalimides as new active lead compounds against Plasmodium falciparum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.91 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL119701 | — | — | 1 | 7.05 |
| CHEMBL1134 | DECAMETHONIUM BROMIDE | 4.0 | 1 | 5.77 |
| CHEMBL122587 | — | — | 1 | 4.92 |
| CHEMBL332524 | HEXAMETHONIUM BROMIDE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL119701 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL1134 | DECAMETHONIUM BROMIDE | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL122587 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL332524 | HEXAMETHONIUM BROMIDE | IC50 | = | 700000.0 | nM | - |