Assay Detail
Functional
CHEMBL1121090
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Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum Dd2 assessed as parasite-specific LDH release after 72 hrs by Malstat assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The bisnaphthalimides as new active lead compounds against Plasmodium falciparum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.42 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL389344 | — | — | 1 | 6.05 |
| CHEMBL1094992 | — | — | 1 | 5.13 |
| CHEMBL233476 | — | — | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL389344 | — | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL1094992 | — | IC50 | = | 7390.0 | nM | 5.13 |
| CHEMBL233476 | — | IC50 | = | 8110.0 | nM | 5.09 |