Assay Detail
Binding
CHEMBL1121208
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Inhibition of human red blood cells protein phosphatase 2A assessed as free phosphate ion release after 60 mins by malachite green method
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of Delta-5,6-norcantharimides: importance of the 5,6-bridge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.81 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48449 | CANTHARIDIN | 4.0 | 1 | 6.05 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | — | 1 | 5.57 |
| CHEMBL1095479 | — | — | 1 | - |
| CHEMBL1095481 | — | — | 1 | - |
| CHEMBL1095480 | — | — | 1 | - |
| CHEMBL1095482 | — | — | 1 | - |
| CHEMBL1095791 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48449 | CANTHARIDIN | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL8327 | DEMETHYL-CANTHARIDIN | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL1095479 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1095481 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1095480 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1095482 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1095791 | — | IC50 | > | 100000.0 | nM | - |