Assay Detail
Binding
CHEMBL1166153
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Saccharomyces cerevisiae uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Orotidine 5'-phosphate decarboxylase (CHEMBL4858) ↗| Type | SINGLE PROTEIN |
| Organism | Saccharomyces cerevisiae S288c |
Publication
Structural determinants for the inhibitory ligands of orotidine-5'-monophosphate decarboxylase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.30 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1164953 | — | — | 1 | 8.30 |
| CHEMBL383923 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1164953 | — | Ki | = | 5.0 | nM | 8.30 |
| CHEMBL383923 | — | Ki | = | 0.009 | nM | - |