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Assay Detail

CHEMBL1166376

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Functional
Antioxidant activity assessed as DPPH radical scavenging activity measured up to 300 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Synthesis of methyl-substituted xanthotoxol to clarify prooxidant effect of methyl on radical-induced oxidation of DNA.
Xiao C, Song ZG, Liu ZQ.
Eur J Med Chem (2010) 45 : 2559 -2566
PubMed 20332056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 4.13 4.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1192 XANTHOTOXOL 1 4.16
CHEMBL1164635 1 4.09
CHEMBL1165808 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1192 XANTHOTOXOL IC50 = 69600.0 nM 4.16
CHEMBL1164635 IC50 = 81500.0 nM 4.09
CHEMBL1165808 IC50 = 118800.0 nM -