Assay Detail
Functional
CHEMBL1167640
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Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxicity of new alkylamino- and phenylamino-containing polyfluorinated derivatives of 1,4-naphthoquinone.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.31 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1164713 | — | — | 1 | 5.62 |
| CHEMBL1164625 | — | — | 1 | 5.60 |
| CHEMBL1164626 | — | — | 1 | 5.39 |
| CHEMBL1164712 | — | — | 1 | 5.07 |
| CHEMBL1164897 | — | — | 1 | 4.87 |
| CHEMBL567184 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1164713 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL1164625 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL1164626 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL1164712 | — | IC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL1164897 | — | IC50 | = | 13400.0 | nM | 4.87 |
| CHEMBL567184 | — | IC50 | = | 173000.0 | nM | - |