Assay Detail
ADMET
CHEMBL1167731
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Cytotoxicity against human MT2 cells after 6 days by XTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MT2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-AIDS agents 82: synthesis of seco-(3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (DCK) derivatives as novel anti-HIV agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.36 | 4.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1163200 | — | — | 1 | 4.41 |
| CHEMBL1164922 | — | — | 1 | 4.41 |
| CHEMBL1164921 | — | — | 1 | 4.41 |
| CHEMBL1164481 | — | — | 1 | 4.40 |
| CHEMBL1163181 | — | — | 1 | 4.40 |
| CHEMBL1164650 | — | — | 1 | 4.25 |
| CHEMBL1163591 | — | — | 1 | 4.23 |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1163200 | — | IC50 | = | 39200.0 | nM | 4.41 |
| CHEMBL1164922 | — | IC50 | = | 39200.0 | nM | 4.41 |
| CHEMBL1164921 | — | IC50 | = | 39200.0 | nM | 4.41 |
| CHEMBL1164481 | — | IC50 | = | 39600.0 | nM | 4.40 |
| CHEMBL1163181 | — | IC50 | = | 39600.0 | nM | 4.40 |
| CHEMBL1164650 | — | IC50 | = | 56500.0 | nM | 4.25 |
| CHEMBL1163591 | — | IC50 | = | 58400.0 | nM | 4.23 |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 1872000.0 | nM | - |