Assay Detail
Binding
CHEMBL1168035
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rice alpha-glucosidase assessed as D-glucose release at pH 5 after 10 to 30 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryza sativa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Probable alpha-glucosidase Os06g0675700 (CHEMBL1163102) ↗| Type | SINGLE PROTEIN |
| Organism | Oryza sativa Japonica Group |
Publication
2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.68 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1163255 | — | — | 1 | 5.00 |
| CHEMBL1163562 | — | — | 1 | 4.35 |
| CHEMBL469844 | — | — | 1 | - |
| CHEMBL1163254 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1163255 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1163562 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL469844 | — | IC50 | = | 171000.0 | nM | - |
| CHEMBL1163254 | — | IC50 | = | 670000.0 | nM | - |