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Assay Detail

CHEMBL1168044

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of jack bean alpha-mannosidase assessed as p-nitrophenol release at pH 4.5 by spectrometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Canavalia ensiformis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease.
Kato A, Yamashita Y, Nakagawa S, Koike Y, Adachi I, Hollinshead J, Nash RJ, Ikeda K, Asano N.
Bioorg Med Chem (2010) 18 : 3790 -3794
PubMed 20457528 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.19 4.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL469844 1 4.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL469844 IC50 = 64000.0 nM 4.19