Assay Detail
Functional
CHEMBL1168168
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Antiviral activity against HRV-1B infected in human HeLa cells assessed as inhibition of viral plaque formation
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human rhinovirus 1B |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
(E)-2-styrylchromones as potential anti-norovirus agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.37 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1164646 | — | — | 1 | 5.96 |
| CHEMBL1164548 | — | — | 1 | 5.29 |
| CHEMBL388823 | — | — | 1 | 5.21 |
| CHEMBL228625 | — | — | 1 | 5.03 |
| CHEMBL1164746 | — | — | 1 | - |
| CHEMBL1164351 | — | — | 1 | - |
| CHEMBL1164352 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1164646 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL1164548 | — | IC50 | = | 5130.0 | nM | 5.29 |
| CHEMBL388823 | — | IC50 | = | 6190.0 | nM | 5.21 |
| CHEMBL228625 | — | IC50 | = | 9290.0 | nM | 5.03 |
| CHEMBL1164746 | — | IC50 | > | 12500.0 | nM | - |
| CHEMBL1164351 | — | IC50 | > | 6250.0 | nM | - |
| CHEMBL1164352 | — | IC50 | > | 3120.0 | nM | - |