Assay Detail
Functional
CHEMBL1175282
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Cytotoxicity against human HepG2 cells after 24 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and cytotoxic activity of fluorinated analogues of Goniothalamus lactones. Impact of fluorine on oxidative processes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.74 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL464443 | GONIOTHALAMIN | — | 1 | 5.80 |
| CHEMBL1170578 | HOWIINOL A | — | 1 | 5.80 |
| CHEMBL1170579 | — | — | 1 | 5.75 |
| CHEMBL1170485 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL464443 | GONIOTHALAMIN | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL1170578 | HOWIINOL A | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL1170579 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL1170485 | — | IC50 | = | 2400.0 | nM | 5.62 |