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Assay Detail

CHEMBL1175287

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Functional
Cytotoxicity against human MDA-MB-231 cells
5
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and cytotoxic activity of fluorinated analogues of Goniothalamus lactones. Impact of fluorine on oxidative processes.
Dumitrescu L, Mai Huong DT, Van Hung N, Crousse B, Bonnet-Delpon D.
Eur J Med Chem (2010) 45 : 3213 -3218
PubMed 20392543 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.27 5.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1170485 4 5.27
CHEMBL464443 GONIOTHALAMIN 1 5.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1170485 IC50 = 5400.0 nM 5.27
CHEMBL1170485 IC50 = 5400.0 nM 5.27
CHEMBL1170485 IC50 = 5400.0 nM 5.27
CHEMBL1170485 IC50 = 5400.0 nM 5.27
CHEMBL464443 GONIOTHALAMIN IC50 = 5400.0 nM 5.27