Assay Detail
Functional
CHEMBL1176793
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Cytotoxicity against human KB cells after 72 hrs by MTT assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of cytotoxic activity of novel anthracene L-rhamnopyranosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 5.89 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1170461 | — | — | 1 | 6.52 |
| CHEMBL1169718 | — | — | 1 | 6.16 |
| CHEMBL464290 | — | — | 1 | 5.96 |
| CHEMBL1171629 | — | — | 1 | 5.96 |
| CHEMBL496999 | FRANGULIN B | — | 1 | 5.68 |
| CHEMBL1171248 | — | — | 1 | 5.08 |
| CHEMBL289277 | EMODIN | — | 1 | - |
| CHEMBL1170469 | — | — | 1 | - |
| CHEMBL1172007 | — | — | 1 | - |
| CHEMBL1172211 | — | — | 1 | - |
| CHEMBL1170462 | — | — | 1 | - |
| CHEMBL1169726 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1170461 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL1169718 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL464290 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL1171629 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL496999 | FRANGULIN B | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL1171248 | — | IC50 | = | 8300.0 | nM | 5.08 |
| CHEMBL289277 | EMODIN | IC50 | > | 20000.0 | nM | - |
| CHEMBL1170469 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1172007 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1172211 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1170462 | — | IC50 | > | 20000.0 | nM | - |
| CHEMBL1169726 | — | IC50 | > | 20000.0 | nM | - |