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Assay Detail

CHEMBL1177385

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against Staphylococcus lentus DSM 6672 after 48 hrs by microtiter plate assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mammaliicoccus lentus
Confidence 1 — Organism
Curated By Autocuration

Target

Mammaliicoccus lentus (CHEMBL613149)
Type ORGANISM
Organism Mammaliicoccus lentus

Publication

Mayamycin, a cytotoxic polyketide from a Streptomyces strain isolated from the marine sponge Halichondria panicea.
Schneemann I, Kajahn I, Ohlendorf B, Zinecker H, Erhard A, Nagel K, Wiese J, Imhoff JF.
J Nat Prod (2010) 73 : 1309 -1312
PubMed 20545334 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.37 5.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL130 CHLORAMPHENICOL 4.0 1 5.64
CHEMBL1173035 MAYAMYCIN 1 5.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL130 CHLORAMPHENICOL IC50 = 2300.0 nM 5.64
CHEMBL1173035 MAYAMYCIN IC50 = 8000.0 nM 5.10