Assay Detail
Binding
CHEMBL1211385
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]NPS from NPS receptor in rat brain superior coliculus after 30 mins
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of a new series of Neuropeptide S receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.84 | 5.84 |
| EC50 | 1 | 5.85 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1210313 | — | — | 2 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1210313 | — | EC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL1210313 | — | IC50 | = | 1440.0 | nM | 5.84 |