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Assay Detail

CHEMBL1219009

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of hepatitis C virus RNA dependent NS5B polymerase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis C virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase.
Giliberti G, Ibba C, Marongiu E, Loddo R, Tonelli M, Boido V, Laurini E, Posocco P, Fermeglia M, Pricl S.
Bioorg Med Chem (2010) 18 : 6055 -6068
PubMed 20638852 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.39 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL448250 1 4.52
CHEMBL476983 1 4.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL448250 IC50 = 30000.0 nM 4.52
CHEMBL476983 IC50 = 55000.0 nM 4.26