Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1219201

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of dopamine D2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

D(2) dopamine receptor (CHEMBL217)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and T-type calcium channel blocking activity of novel diphenylpiperazine compounds, and evaluation of in vivo analgesic activity.
Kam YL, Rhee HK, Rhim H, Back SK, Na HS, Choo HY.
Bioorg Med Chem (2010) 18 : 5938 -5944
PubMed 20659804 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.54 7.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1423 PIMOZIDE 4.0 1 7.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1423 PIMOZIDE Kd = 29.0 nM 7.54