Assay Detail
Binding
CHEMBL1220333
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to HCV 2AP54-labelled IRES subdomain 2a RNA in presence of 0.3 mM Mg2+ by FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Internal ribosome entry site (IRES) (CHEMBL612412) ↗| Type | NUCLEIC-ACID |
| Organism | Hepacivirus hominis |
Publication
Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.58 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223720 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223720 | — | EC50 | = | 260.0 | nM | 6.58 |