Assay Detail
Functional
CHEMBL1220476
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Inhibition of HCV 1b replicon translation in human HuH7 cells transfected with BM4-5 FEO HCV replicon RNA after 4 hrs by luciferase reporter assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.40 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL223720 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL223720 | — | IC50 | = | 4000.0 | nM | 5.40 |