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Assay Detail

CHEMBL1220933

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Mycobacterium tuberculosis H37Rv FACL28
3
Total Activities
2
Compounds Tested
3
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mycobacterium tuberculosis H37Rv
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis.
Arora P, Goyal A, Natarajan VT, Rajakumara E, Verma P, Gupta R, Yousuf M, Trivedi OA, Mohanty D, Tyagi A, Sankaranarayanan R, Gokhale RS.
Nat Chem Biol (2009) 5 : 166 -173
PubMed 19182784 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Inhibition 1 - -
Ki 1 5.83 5.83
IC50 1 5.92 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1213327 COENZYME_A 3.0 2 5.92
CHEMBL1213367 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1213327 COENZYME_A IC50 = 1200.0 nM 5.92
CHEMBL1213327 COENZYME_A Ki = 1480.0 nM 5.83
CHEMBL1213367 Inhibition - % -