Assay Detail
Functional
CHEMBL1225656
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Cytotoxicity against human SKOV3 cells by SRB assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Lactarane sesquiterpenoids from Lactarius subvellereus and their cytotoxicity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 9.00 |
| CHEMBL1223947 | SUBVELLEROLACTONES B | — | 1 | - |
| CHEMBL1223948 | SUBVELLEROLACTONES D | — | 1 | - |
| CHEMBL1221436 | SUBVELLEROLACTONES E | — | 1 | - |
| CHEMBL1223949 | 5-DESOXYLACTAROLIDE B | — | 1 | - |
| CHEMBL1223950 | FURANDIOL | — | 1 | - |
| CHEMBL1224063 | LACTARORUFIN A | — | 1 | - |
| CHEMBL1224064 | LACTAROLIDE A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL1223947 | SUBVELLEROLACTONES B | IC50 | > | 30000.0 | nM | - |
| CHEMBL1223948 | SUBVELLEROLACTONES D | IC50 | > | 30000.0 | nM | - |
| CHEMBL1221436 | SUBVELLEROLACTONES E | IC50 | > | 30000.0 | nM | - |
| CHEMBL1223949 | 5-DESOXYLACTAROLIDE B | IC50 | > | 30000.0 | nM | - |
| CHEMBL1223950 | FURANDIOL | IC50 | > | 30000.0 | nM | - |
| CHEMBL1224063 | LACTARORUFIN A | IC50 | > | 30000.0 | nM | - |
| CHEMBL1224064 | LACTAROLIDE A | IC50 | > | 30000.0 | nM | - |