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Assay Detail

CHEMBL1228764

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of GGTase1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Therapeutic intervention based on protein prenylation and associated modifications.
Gelb MH, Brunsveld L, Hrycyna CA, Michaelis S, Tamanoi F, Van Voorhis WC, Waldmann H.
Nat Chem Biol (2006) 2 : 518 -528
PubMed 16983387 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.10 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1222043 1 8.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1222043 IC50 = 8.0 nM 8.10