Assay Detail
Functional
CHEMBL1243640
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Inhibition of 50 nM rapamycin-mediated cytostatic effect in yeast BY4742 after 48 to 96 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Saccharomyces cerevisiae |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.68 | 6.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL404954 | — | — | 1 | 6.38 |
| CHEMBL312487 | — | — | 1 | 4.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL404954 | — | EC50 | = | 412.0 | nM | 6.38 |
| CHEMBL312487 | — | EC50 | = | 10400.0 | nM | 4.98 |