Assay Detail
Functional
CHEMBL1245075
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Antiviral activity against Hepatitis C virus genotype 1a containing NS3/con1 protease mutant by TaqMan-based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.80 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4525964 | VANIPREVIR | 3.0 | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4525964 | VANIPREVIR | EC50 | = | 1.6 | nM | 8.80 |