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Assay Detail

CHEMBL1246372

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of hedgehog receptor mediated Ptch1 transcription
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Modulators of the hedgehog signaling pathway.
Heretsch P, Tzagkaroulaki L, Giannis A.
Bioorg Med Chem (2010) 18 : 6613 -6624
PubMed 20708941 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL254129 CYCLOPAMINE 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL254129 CYCLOPAMINE EC50 = 300.0 nM 6.52