Assay Detail
Binding
CHEMBL1246811
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX2
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
3-Formylchromones: potential antiinflammatory agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.98 | 6.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL6 | INDOMETHACIN | 4.0 | 1 | 6.17 |
| CHEMBL524686 | — | — | 1 | 4.59 |
| CHEMBL519521 | — | — | 1 | 4.18 |
| CHEMBL1241823 | — | — | 1 | - |
| CHEMBL1241822 | — | — | 1 | - |
| CHEMBL1240658 | — | — | 1 | - |
| CHEMBL25 | ASPIRIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL6 | INDOMETHACIN | IC50 | = | 670.0 | nM | 6.17 |
| CHEMBL524686 | — | IC50 | = | 25430.0 | nM | 4.59 |
| CHEMBL519521 | — | IC50 | = | 65720.0 | nM | 4.18 |
| CHEMBL1241823 | — | IC50 | = | 203690.0 | nM | - |
| CHEMBL1241822 | — | IC50 | = | 802320.0 | nM | - |
| CHEMBL1240658 | — | IC50 | > | 1000000.0 | nM | - |
| CHEMBL25 | ASPIRIN | IC50 | = | 1000000.0 | nM | - |