Assay Detail
Functional
CHEMBL1248952
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Antitumor activity against human MDA-MB-231 cells after 6 days by SRB assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.59 | 4.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL197892 | — | — | 1 | 4.90 |
| CHEMBL1241129 | — | — | 1 | 4.76 |
| CHEMBL1241237 | — | — | 1 | 4.74 |
| CHEMBL1241127 | SALICYLALDOXIME | — | 1 | 4.72 |
| CHEMBL1241236 | — | — | 1 | 4.71 |
| CHEMBL165 | RESVERATROL | 3.0 | 1 | 4.69 |
| CHEMBL1241128 | — | — | 1 | 4.34 |
| CHEMBL1241235 | — | — | 1 | 4.32 |
| CHEMBL1241264 | — | — | 1 | 4.17 |
| CHEMBL45564 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL197892 | — | IC50 | = | 12700.0 | nM | 4.90 |
| CHEMBL1241129 | — | IC50 | = | 17400.0 | nM | 4.76 |
| CHEMBL1241237 | — | IC50 | = | 18100.0 | nM | 4.74 |
| CHEMBL1241127 | SALICYLALDOXIME | IC50 | = | 19200.0 | nM | 4.72 |
| CHEMBL1241236 | — | IC50 | = | 19400.0 | nM | 4.71 |
| CHEMBL165 | RESVERATROL | IC50 | = | 20500.0 | nM | 4.69 |
| CHEMBL1241128 | — | IC50 | = | 46100.0 | nM | 4.34 |
| CHEMBL1241235 | — | IC50 | = | 47400.0 | nM | 4.32 |
| CHEMBL1241264 | — | IC50 | = | 67600.0 | nM | 4.17 |
| CHEMBL45564 | — | IC50 | > | 100000.0 | nM | - |