Assay Detail
Binding
CHEMBL1249604
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Inhibition of Integrin alpha-4-beta-1-mediated adhesion in human jurkat cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 10.09 | 10.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1241140 | — | — | 1 | 10.66 |
| CHEMBL88478 | — | — | 1 | 9.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1241140 | — | IC50 | = | 0.022 | nM | 10.66 |
| CHEMBL88478 | — | IC50 | = | 0.3 | nM | 9.52 |