Assay Detail
Binding
CHEMBL1250067
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant polo-like kinase 1 activity by SDS-PAGE
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase PLK1 (CHEMBL3024) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Probing cell-division phenotype space and Polo-like kinase function using small molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.58 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1242101 | — | — | 1 | 6.05 |
| CHEMBL492008 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1242101 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL492008 | — | IC50 | = | 8000.0 | nM | 5.10 |