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Assay Detail

CHEMBL1250100

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Myc-Jun protein - protein interaction in chicken embryo fibroblasts assessed as inhibition of cell focus formation11
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Gallus gallus
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Myc proto-oncogene protein/Transcription factor AP-1 (CHEMBL3885607)
Type PROTEIN-PROTEIN INTERACTION
Organism Gallus gallus

Publication

Diversity-oriented synthesis: exploring the intersections between chemistry and biology.
Tan DS.
Nat Chem Biol (2005) 1 : 74 -84
PubMed 16408003 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.82 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL405759 1 4.82
CHEMBL1627240 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL405759 IC50 = 15000.0 nM 4.82
CHEMBL1627240 IC50 = 15000.0 nM 4.82