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Assay Detail

CHEMBL1253098

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse L1210 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type L1210
Confidence 1 — Organism
Curated By Autocuration

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Novel approaches for targeting thymidylate synthase to overcome the resistance and toxicity of anticancer drugs.
Garg D, Henrich S, Salo-Ahen OM, Myllykallio H, Costi MP, Wade RC.
J Med Chem (2010) 53 : 6539 -6549
PubMed 20527892 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.16 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1253498 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1253498 IC50 = 7000.0 nM 5.16