Assay Detail
Binding
CHEMBL1253102
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]vasopressin from vasopressin V1a receptor in human liver tissue
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Oral oxytocin antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.12 | 9.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL445816 | — | — | 1 | 9.19 |
| CHEMBL1253853 | — | — | 1 | 6.75 |
| CHEMBL1254117 | — | — | 1 | 5.85 |
| CHEMBL341339 | — | — | 1 | 5.80 |
| CHEMBL24781 | — | — | 1 | 5.50 |
| CHEMBL306645 | — | — | 1 | 5.50 |
| CHEMBL296908 | — | — | 1 | 4.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL445816 | — | Ki | = | 0.65 | nM | 9.19 |
| CHEMBL1253853 | — | Ki | = | 180.0 | nM | 6.75 |
| CHEMBL1254117 | — | Ki | = | 1410.0 | nM | 5.85 |
| CHEMBL341339 | — | Ki | = | 1600.0 | nM | 5.80 |
| CHEMBL24781 | — | Ki | = | 3200.0 | nM | 5.50 |
| CHEMBL306645 | — | Ki | = | 3200.0 | nM | 5.50 |
| CHEMBL296908 | — | Ki | = | 52000.0 | nM | 4.28 |