Assay Detail
Binding
CHEMBL1259263
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]Spiperone from human dopamine D3 receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel pyridylmethylamines as highly selective 5-HT(1A) superagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.93 | 5.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1259241 | — | — | 1 | 5.06 |
| CHEMBL45305 | BEFIRADOL | 2.0 | 1 | 5.00 |
| CHEMBL1258999 | — | — | 1 | 4.92 |
| CHEMBL1259071 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1259241 | — | Ki | = | 8700.0 | nM | 5.06 |
| CHEMBL45305 | BEFIRADOL | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL1258999 | — | Ki | = | 12000.0 | nM | 4.92 |
| CHEMBL1259071 | — | Ki | = | 19000.0 | nM | 4.72 |