Assay Detail

CHEMBL1259949

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Functional

Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay

ChEMBL ↗

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Target

MCF7 (CHEMBL387) ↗

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Primary target MCF7

CHEMBL387

Anchored from Assay target.

Protein identity MCF7

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	MCF7
Confidence	1 — Organism
Curated By	Autocuration

Target

MCF7 (CHEMBL387) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Dihydro-resveratrol--a potent dietary polyphenol.

Gakh AA, Anisimova NY, Kiselevsky MV, Sadovnikov SV, Stankov IN, Yudin MV, Rufanov KA, Krasavin MY, Sosnov AV.
Bioorg Med Chem Lett (2010) 20 : 6149 -6151
PubMed 20813524 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	8.00	10.00

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL111234	DIHYDRORESVERATROL	—	1	10.00
CHEMBL44	GENISTEIN	2.0	1	6.00

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL111234	DIHYDRORESVERATROL	IC50	=	0.1	nM	10.00
CHEMBL44	GENISTEIN	IC50	=	1000.0	nM	6.00