Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1261995

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 infected in O+ human erythrocytes by [3H]hypoxanthine incorporation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Potent antimalarial activity of histone deacetylase inhibitor analogues.
Andrews KT, Tran TN, Lucke AJ, Kahnberg P, Le GT, Boyle GM, Gardiner DL, Skinner-Adams TS, Fairlie DP.
Antimicrob Agents Chemother (2008) 52 : 1454 -1461
PubMed 18212103 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.03 6.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL320497 SUBEROHYDROXAMIC ACID 1 6.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL320497 SUBEROHYDROXAMIC ACID IC50 = 940.0 nM 6.03