Assay Detail
Functional
CHEMBL1267140
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Antiplasmodial activity against Plasmodium falciparum WE2 after 72 hrs by SYBR green assay
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.92 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1200517 | DIHYDROERGOTAMINE MESYLATE | 4.0 | 1 | 6.75 |
| CHEMBL585 | TRIAMTERENE | 4.0 | 2 | 4.35 |
| CHEMBL22 | TRIMETHOPRIM | 4.0 | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1200517 | DIHYDROERGOTAMINE MESYLATE | IC50 | = | 179.9 | nM | 6.75 |
| CHEMBL585 | TRIAMTERENE | IC50 | = | 44555.0 | nM | 4.35 |
| CHEMBL585 | TRIAMTERENE | IC50 | = | 44555.0 | nM | 4.35 |
| CHEMBL22 | TRIMETHOPRIM | IC50 | = | 61785.0 | nM | 4.21 |