Assay Detail
Binding
CHEMBL1267672
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Beta-lactamase OXA-14 expressed in Escherichia coli BL21 (DE3) by nitrocefin hydrolysis assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Penicillin sulfone inhibitors of class D beta-lactamases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.12 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1257120 | — | — | 1 | 5.85 |
| CHEMBL1257121 | — | — | 1 | 5.40 |
| CHEMBL777 | CLAVULANIC ACID | 4.0 | 1 | 4.72 |
| CHEMBL404 | TAZOBACTAM | 4.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1257120 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL1257121 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL777 | CLAVULANIC ACID | Ki | = | 19000.0 | nM | 4.72 |
| CHEMBL404 | TAZOBACTAM | Ki | = | 30000.0 | nM | 4.52 |